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蛋白质/抗原/多肽 >> 重组蛋白
重组Nebulette蛋白(NEBL)
重组Nebulette蛋白(NEBL)图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:重组肌动蛋白结合蛋白Z盘状蛋白
Recombinant NEBL
产品介绍
基因名:

NEBL


产品别名:

C10orf113; LASP2; LNEBL; bA165O3.1; NEBL; nebulette; nebulette; nebulette; LIM and SH3 protein 2; LIM-nebulette; actin-binding Z-disk protein; Nebulette蛋白(NEBL); 肌动蛋白结合蛋白Z盘状蛋白;


背景信息:
Nebulette binds to actin and plays an important role in Z-disk assembly. It is a cardiac homolog of nebulin and its expression is abundant in cardiac muscle. Nebulette defects are assocated with non-familial idiopathic cardiacmyopathy.
Nebulin and nebulette are homologous thin-filament associated proteins expressed in skeletal and cardiac muscles, respectively. Nebulette, unlike nebulin, is confined to the Z-disc region of the sarcomere and does not span the whole thin filament length. Nebulette colocalizes with α-actinin in the pre-, nascent, and mature myofibrils. A polymorphism in the actin-binding motif of nebulette is a genetic marker of susceptibility to nonfamilial idiopathic dilated cardiomyopathy (IDC), characterized by a thin-walled heart and systolic dysfunction.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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