Biotin-PEG3-azide is a PEG-basedPROTAClinkercan be used in the synthesis ofPROTACs.

Biotin-C2-PEG3-azide is a biotin with the azide tag, it can be conjugated to antiviral inhibitors, for example, RYL-634, which shows excellent broad-spectrum inhibition activity against various pathogenic viruses, including hepatitis C virus, dengue virus, Zika virus, chikungunya virus, enterovirus^[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

444.55

Solid

C₁₈H₃₂N₆O₅S

875770-34-6

Room temperature in continental US; may vary elsewhere.