(S,R,S)-AHPC-phenol-C4-NH2 (VH032-phenol-C4-NH2) dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used in PROTAC technology^[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[2].

632.64

Solid

C₂₈H₄₃Cl₂N₅O₅S

2376990-26-8

Room temperature in continental US; may vary elsewhere.

DMSO : 100 mg/mL(158.07 mM;Need ultrasonic)

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