PI3K-IN-34 (Compound 6g) is a highly selectivePI3Kinhibitor withIC₅₀values of 11.73, 6.09 and 11.18 μM for PI3K-α、PI3K-β and PI3K-δ , respectively. PI3K-IN-34 arrests cell cycle at G2/M phase and inducesapoptosis. PI3K-IN-34 can be used in leukemia research^[1].

PI3K-IN-34 (Compound 6g) (10 μM, 48 hours) possess potent antiproliferative activity can inhibit proliferation of Leukemia SR cell lines in vitro^[1].
PI3K-IN-34 (Compound 6g) induces cell cycle arrest toward the G2-M phase (45.75%) and leads to DNA synthesis and apoptosis^[1].
PI3K-IN-34 (Compound 6g) (10 μM, 48 hours) results in apoptotic with 22.83% of cells in the early and latest age^[1].

430.46

C₂₃H₂₂N₆O₃

2458163-94-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.