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1-Deoxynojirimycin hydrochloride
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
1-Deoxynojirimycin hydrochloride图片
CAS NO:73285-50-4
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
Duvoglustat hydrochloride
产品介绍
1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) 是一种口服有效的 α-葡萄糖苷酶 (α-glucosidase) 抑制剂。1-Deoxynojirimycin hydrochloride 抑制餐后血糖，预防糖尿病。1-Deoxynojirimycin hydrochloride 具有降血糖、减肥和抗病毒的作用。
生物活性

1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) is a potent and orally activeα-glucosidaseinhibitor. 1-Deoxynojirimycin hydrochloride suppresses postprandial blood glucose and is widely used for diabetes mellitus. 1-Deoxynojirimycin hydrochloride possesses antihyperglycemic, anti-obesity, and antiviral features[1][2].

体内研究
(In Vivo)

1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) (20-80 mg/kg; i.v.; daily for four weeks) shows anti-obesity effect[3].
1-Deoxynojirimycin hydrochloride significantly improves insulin sensitivity via activating insulin signaling PI3K/AKT pathway in skeletal muscle of db/db mice[3].

Animal Model:db/db mice[3]
Dosage:20, 40, 80 mg/kg
Administration:Intravenously; daily for four weeks
Result:Significantly reduced body weight, blood glucose and serum insulin levels; Improved glucose tolerance and insulin tolerance.
Clinical Trial
分子量

199.63

Formula

C6H14ClNO4

CAS 号

73285-50-4

中文名称

去氧野艽霉素盐酸盐

结构分类
  • Saccharides
  • Monosaccharides
来源
  • Plants
  • Commelinaceae
  • Commelina communis
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.