Coumarin boronic acid (CBA) is a fluorescent probe that can be used to detect peroxynitrite, hypochlorous acid, and hydrogen peroxide.
Cas No. | 1357078-03-5 |
Canonical SMILES | O=C1OC2=CC(B(O)O)=CC=C2C=C1 |
分子式 | C9H7BO4 |
分子量 | 190 |
溶解度 | DMF: 11 mg/ml,DMSO: 3 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 1 mg/ml |
储存条件 | Store at -20℃, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Coumarin boronic acid (CBA) is a fluorescent probe that can be used to detect peroxynitrite , hypochlorous acid, and hydrogen peroxide.It reacts with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s) and moderately faster rate than hypochlorous acid. Peroxynitrite oxidizes CBA into the fluorescent product 7-hydroxycoumarin (COH), which displays excitation/emission maxima of 332/470 nm, respectively. |