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DEPMPO-biotin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DEPMPO-biotin图片
CAS NO:936224-52-1
包装与价格:
包装价格(元)
25μg电议
50μg电议
100μg电议
250μg电议

产品介绍
Cas No.936224-52-1
Canonical SMILESCCOP(=O)(OCC)C1(C)[C@H](COC(=O)NCCCNC(=O)CCCC[C@H]2SC[C@H]3NC(=O)N[C@@H]23)CC=[N+]1[O-]
分子式C24H42N5O8PS
分子量591.7
溶解度Ethanol: 10 mg/ml,Water: 1 mg/ml
储存条件Store at -80℃, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

DEPMPO is a nitrone that is used to spin trap reactive O-, N-, S-, and C-centered radicals and allow their characterization when used in association with electron spin resonance. It is noted for the stability of adducts formed. DEPMPO can be used in vitro or in vivo, as it crosses lipid bilayer membranes and is a good trapping agent in biological systems. DEPMPO-biotin is a biotinylated form of DEPMPO which retains the outstanding persistency of its adducts. The biotin moiety offers an effective means for monitoring biodistribution in cells, tissues, and organs when used with an avidin-conjugated reporter. Importantly, DEPMPO-biotin binds free radicals, such as S-nitroso groups, on proteins, producing adducts that can be analyzed via the biotin tag. This direct labeling of S-nitrosothiols (SNO) thus serves as an effective alternative to the more cumbersome biotin-switch method for monitoring SNO formation.