Keap1-Nrf2-IN-1 TFA (compound35) is aKelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 (Keap1-Nrf2) protein-protein interactioninhibitor, and with anIC₅₀of 43 nM for Keap1 protein. Keap1-Nrf2-IN-1 TFA activates Nrf2-regulated cytoprotective response and antagonizes acetaminophen-induced liver injury both in cellular and in vivo models^[1].

IC50: 43 nM (Keap1 protein)^[1]

598.54

C₂₆H₂₅F₃N₂O₉S

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

DMSO : 83.33 mg/mL(139.22 mM;Need ultrasonic)