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Autocamtide-2-related inhibitory peptide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:167114-91-2
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Autocamtide-2-related inhibitory peptide 是高度特异性的、CaMKII的有效抑制剂,其IC50值为 40 nM。
生物活性

Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor ofCaMKIIwith anIC50of 40 nM.

IC50& Target

IC50: 40 nM (CaMKII)[1].

体外研究
(In Vitro)

It is found that Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC50of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used[1].

分子量

1497.74

Formula

C64H116N22O19

CAS 号

167114-91-2

Sequence

Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu

Sequence Shortening

KKALRRQEAVDAL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.