您好，欢迎来到试剂仪器网！ [登录] [免费注册]
试剂仪器网
发布求购
位置：首页 > 产品库 > MtbHU-IN-1
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
MtbHU-IN-1
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
MtbHU-IN-1图片
CAS NO:59736-84-4
包装与价格：
包装价格(元)
250mg电议
500mg电议

产品介绍
MtbHU-IN-1是结合分枝杆菌核型相关蛋白HU(MtbHU)的抑制剂，其对野生型MtbHU蛋白的结合Kd值为98nM.
Cas No.59736-84-4
Canonical SMILESO=S(NC1=CC=C(C=C1)C(O)=O)(C2=CC(NC(C3=CC=C(OC)C=C3)=O)=CC=C2/C=C/C4=CC=C(NC(C5=CC=C(OC)C=C5)=O)C=C4S(NC6=CC=C(C=C6)C(O)=O)(=O)=O)=O
分子式C44H36N4O12S2
分子量876.91
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

MtbHU-IN-1 is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with a Kd of 98 nM for binding to WT MtbHU.

MtbHU-IN-1 (SD4) is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with Kds of 98 nM, 760 nM, 980 nM, 340 nM and 730 nM for WT and mutant MtbHUs, respectively[1].

[1]. Bhowmick T, et al. Targeting Mycobacterium tuberculosis nucleoid-associated protein HU with structure-based inhibitors. Nat Commun. 2014 Jun 11;5:4124.