您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Caerulomycin A(Cerulomycin)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Caerulomycin A(Cerulomycin)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Caerulomycin A(Cerulomycin)图片
CAS NO:21802-37-9
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1mg电议
5mg电议
10mg电议

产品介绍
Caerulomycin A (Cerulomycin) (Cerulomycin; Caerulomycin) 是一种抗真菌化合物,可诱导 T 细胞生成,通过抑制干扰素-γ-诱导的 STAT1 信号传导增强 TGF-β-Smad3 蛋白信号传导。
Cas No.21802-37-9
别名浅蓝霉素,Cerulomycin; Caerulomycin
Canonical SMILESCOC1=CC(C2=NC=CC=C2)=NC(/C=N/O)=C1
分子式C12H11N3O2
分子量229.23
溶解度DMSO : 150 mg/mL (654.36 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Caerulomycin A (Cerulomycin) is a bipyridyl compound, induces generation of T cells, enhances TGF-β-Smad3 protein signaling via suppressing interferon-γ-induced STAT1 signaling. Antifungal and antibiotic activity, and used in autoimmune diseases[1].

[1]. Gurram RK, et al. Caerulomycin A enhances transforming growth factor-β (TGF-β)-Smad3 protein signaling by suppressing interferon-γ (IFN-γ)-signal transducer and activator of transcription 1 (STAT1) protein signaling to expand regulatory T cells (Tregs). J Biol Chem. 2014 Jun 20;289(25):17515-28.