FFN511 is a potent fluorescent false neurotransmitters (FFNs) that targetsneuronal vesicularmonoamine transporter2 (VMA T2). FFN511 inhibits serotonin binding toVMA T2-containing membranes with anIC₅₀of 1 μM. FFN511 directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices^[1][2].

FFN511 (350 nM; 30 min) accumulats in a pattern consistent with LDCVs in cultured mouse chromaffin cells, and the accumulation is abolished by the lipophilic base chloroquine^[1].

284.35

C₁₇H₂₀N₂O₂

1004548-96-2

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