TAK 21d (compound 21d) 是一种有效的、具有口服活性并能穿过血脑屏障脂肪酸酰胺水解酶 (FAAH) 的抑制剂,对 hFAAH 和 rFAAH 的 IC50 分别为 0.72 和 0.28 nM。
Cas No. | 1143578-94-2 |
化学名 | 4-(4-(3,4-difluorophenyl)pyrimidin-2-yl)-N-(pyridazin-3-yl)piperazine-1-carboxamide |
Canonical SMILES | FC1=CC=C(C2=NC(N3CCN(C(NC4=CC=CN=N4)=O)CC3)=NC=C2)C=C1F |
分子式 | C19H17F2N7O |
分子量 | 397.38 |
溶解度 | <7.95mg/ml in 1eq. HCl |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |