您好，欢迎来到试剂仪器网！ [登录] [免费注册]
试剂仪器网
发布求购
位置：首页 > 产品库 > Fomepizole
立即咨询
咨询类型：
     
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
 
Fomepizole
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Fomepizole图片
CAS NO:7554-65-6
包装与价格：
包装价格(元)
100mg电议
500mg电议

产品介绍
Fomepizole (4-Methylpyrazole) 是一种有效的细胞色素 P450 (CYP2E1) 抑制剂。
Cas No.7554-65-6
别名甲吡唑; 4-Methylpyrazole
化学名4-methyl-1H-pyrazole
Canonical SMILESCC1=CNN=C1
分子式C4H6N2
分子量82.1
溶解度≥ 8.2mg/mL in Water
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase which plays a key role in the metabolism of ethylene glycol and methanol.

References:
[1]. Casavant MJ. Fomepizole in the treatment of poisoning. Pediatrics. 2001 Jan;107(1):170.
[2]. Lepik KJ, et al. Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizole. Ann Emerg Med. 2009 Apr;53(4):439-450.e10.