| CAS NO: | 110-94-1 |
| 包装: | 1g |
| 市场价: | 446元 |
| Cas No. | 110-94-1 |
| 别名 | 戊二酸 |
| Canonical SMILES | O=C(O)CCCC(O)=O |
| 分子式 | C5H8O4 |
| 分子量 | 132.12 |
| 溶解度 | DMSO: 125 mg/mL (946.11 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Glutaric acid induces oxidative stress in brain of young rats. Glutaric acid (GA) at concentrations of 1 and 2 mM is able to reduce TRAP measurement by up to 28% in a dose-dependent manner (β=0.77; P<0.001). Furthermore, a significantly inverse correlation is also verified between chemiluminescence and TRAP (β=0.81; P<0.001). Glutaric acid does not alter the activities of Cat and SOD, but strongly inhibits (up to 46%) the activity of GPx even at the lower concentration used (0.5 mM). It is observed that the metabolite inhibits this activity in a dose-dependent manner at concentrations as low as 0.05 mM[1]. [1]. de Oliveira Marques F, et al. acid induces oxidative stress in brain of young rats. Brain Res. 2003 Feb 21;964(1):153-8. |
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