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(R,S)-Ivosidenib((R,S)-AG-120)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(R,S)-Ivosidenib((R,S)-AG-120)图片
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
(R,S)-Ivosidenib是一种异柠檬酸脱氢酶(IDH1)抑制剂。
Canonical SMILESFC1(F)CC(NC([C@H](N(C2=CC(F)=CN=C2)C([C@@H](N3C4=NC=CC(C#N)=C4)CCC3=O)=O)C5=CC=CC=C5Cl)=O)C1
分子式C28H22ClF3N6O3
分子量582.96
溶解度DMSO : 3.33 mg/mL (5.71 mM);Water :< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(R,S)-Ivosidenib is a inhibitor of Isocitrate Dehydrogenase (IDH1).Target: IDH1

[1]. Agresta Samuel V, et al. (S)-N-((S)-1-(2-Chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide as therapeutically active compound for treating cancer characterized by a [2]. Gu Chong-Hui, et al. Pharmaceutical compositions of therapeutically active compounds comprising (S)-N-((S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide for