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7α-hydroxy-4-Cholesten-3-one
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
7α-hydroxy-4-Cholesten-3-one图片
CAS NO:3862-25-7
包装:1mg
市场价:3916元

产品介绍
7α-hydroxy-4-Cholesten-3-one 是从胆固醇合成胆汁酸的中间体。
Cas No.3862-25-7
别名7-羟基-4-胆甾烯-3-酮
化学名7α-hydroxy-cholest-4-en-3-one
Canonical SMILESO=C1CC[C@@]2(C)C(C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C)C)=C1
分子式C27H44O2
分子量400.6
溶解度Slightly soluble in methanol and chloroform
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

7α-hydroxy-4-Cholesten-3-one is a metabolite of 7α-hydroxy cholesterol and an intermediate in the biosynthesis of bile acids.[1] Plasma levels of 7α-hydroxy-4-cholesten-3-one positively correlate with the rate of bile acid synthesis in humans and are increased in patients following ileal resection.[2]

Reference:
[1]. Russell, D.W. The enzymes, regulation, and genetics of bile acid synthesis. Annu. Rev. Biochem. 72, 137-174 (2003).
[2]. Axelson, M., Aly, A., and Sjovall, J. Levels of 7α-hydroxy-4-cholesten-3-one in plasma reflect rates of bile acid synthesis in man. FEBS Lett. 239(2), 324-328 (1988).