Lidocaine-d10 N-Oxide is the deuterium labeled Lidocaine. Lidocaine (Lignocaine) inhibitssodium channelsinvolving complex voltage and using dependence^[1]. Lidocaine decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation ofMEK/ERKandNF-κBsignaling pathways. Lidocaine is an amide derivative and has potential for the research of ventricular arrhythmia^[2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

260.40

C₁₄H₁₂D₁₀N₂O₂

851528-10-4

利多卡因 d10（N 氧化物）

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.