CAS NO: | 512-04-9 |
包装 | 价格(元) |
100mg | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
生物活性 | Diosgenin, a steroidal saponin, can inhibitSTAT3signaling pathway[1]. Diosgenin is an exogenous activator ofPdia3/ERp57[2]. | ||||||||||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | In MC65 cells, a cellular AD model, diosgenin exhibited weak protective abilities at 1 μM, may represent a good candidate as a steroidal moiety in our bivalent compounds against AD pathology[3]. Diosgenin inhibits the constitutive activation of STAT3 in C3A cells in a dose-dependent manner, with maximum inhibition occurring at around 100 μM[1]. | ||||||||||||||||
体内研究 (In Vivo) | Diosgenin treatment significantly reduces fasted and refed blood glucose level in HF dietfed mice. Diosgenin treatment significantly reduces blood glucose level in IPGTT test, compared with that of HF diet-fed mice[4]. | ||||||||||||||||
分子量 | 414.62 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C27H42O3 | ||||||||||||||||
CAS 号 | 512-04-9 | ||||||||||||||||
中文名称 | 薯蓣皂素;薯蓣皂甙元;薯蓣皂苷元;地奥配质;薯芋皂苷配基;薯芋皂素 | ||||||||||||||||
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: Ethanol : 6.67 mg/mL(16.09 mM;Need ultrasonic) DMSO : 1 mg/mL(2.41 mM;Need ultrasonic) H2O :< 0.1 mg/mL (ultrasonic;warming;heat to 60℃)(insoluble) 配制储备液
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以下溶剂前显示的百
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