Betahistine-d3 dihydrochloride is the deuterium labeled Betahistine dihydrochloride. Betahistine dihydrochloride is an orally activehistamine H1 receptoragonist and aH3 receptorantagonist^[1]. Betahistine dihydrochloride is used for the study of rheumatoid arthritis (RA)^[3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

212.13

Solid

C₈H₁₁D₃Cl₂N₂

244094-72-2

盐酸倍他司汀 d3 (双盐酸盐)

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)