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COX-2-IN-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
COX-2-IN-2图片
CAS NO:134729-13-8
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
COX-2-IN-2 是选择性的,诱导型的COX2抑制剂,IC50值为0.24 μM。COX-2-IN-2 是具有抗炎和止痛活性的抗炎物。
生物活性

COX-2-IN-2 is a selective and inducibleCOX2inhibitor with anIC50of 0.24 μM. COX-2-IN-1 is an anti-inflammatory compound with anti-inflammatory and analgesic activities.

IC50& Target[1]

COX-2

240 nM (IC50)

体外研究
(In Vitro)

COX-2-IN-2 shows no COX-1 inhibition even at 100μM[1].

体内研究
(In Vivo)

COX-2-IN-2 has oral ED50values of 0.030 and 0.47mg/kg on adjuvant-induced arthritis and collagen-induced arthritis, respectively, and an ED30value of 7.4mg/kg in the yeast-induced hyperalgesia (Randall-Selitto) assay. COX-2-IN-2 shows good analgesic activity and no ulcerogenicity[1].

分子量

341.36

Formula

C17H12FN3O2S

CAS 号

134729-13-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.