CAS NO: | 134729-13-8 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | COX-2-IN-2 is a selective and inducibleCOX2inhibitor with anIC50of 0.24 μM. COX-2-IN-1 is an anti-inflammatory compound with anti-inflammatory and analgesic activities. | |
IC50& Target[1] |
| |
体外研究 (In Vitro) | COX-2-IN-2 shows no COX-1 inhibition even at 100μM[1]. | |
体内研究 (In Vivo) | COX-2-IN-2 has oral ED50values of 0.030 and 0.47mg/kg on adjuvant-induced arthritis and collagen-induced arthritis, respectively, and an ED30value of 7.4mg/kg in the yeast-induced hyperalgesia (Randall-Selitto) assay. COX-2-IN-2 shows good analgesic activity and no ulcerogenicity[1]. | |
分子量 | 341.36 | |
Formula | C17H12FN3O2S | |
CAS 号 | 134729-13-8 | |
运输条件 | Room temperature in continental US; may vary elsewhere. | |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |