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Taraxerol acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Taraxerol acetate图片
CAS NO:2189-80-2
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
醋酸蒲公英霜
产品介绍
Taraxerol acetate 是COX-1COX-2抑制剂, IC50值分别为 116.3 μM 和 94.7μM。Taraxerol acetate 具有抗癌作用并诱导细胞凋亡(apoptosis)。
生物活性

Taraxerol acetate is aCOX-1andCOX-2inhibitor with IC50values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cellapoptosis[1].

IC50& Target[1]

COX-1

116.3 μM (IC50)

COX-2

94.7 μM (IC50)

体外研究
(In Vitro)

Taraxerol acetate(10-150 μM; 24 or 48 hours) induces a dose- and time-dependent cytotoxic effects in the U87 cells, exhibits IC50values of 34.2 and 28.4 μM, at 24 and 48 h, respectively[2].
Taraxerol acetate(10, 50 and 150 μM; 24 hours) induces cell apoptosis, the percentage of apoptotic cells increased from 7.3% in the control cells, to 16.1, 44.1 and in the 10, 50 and 150 μM taraxerol acetate-treated cells, respectively. Furthermore, taraxerol acetate treatment led to sub-G1 cell cycle arrest with a corresponding decrease in the number of S-phase cells[2].

分子量

468.75

Formula

C32H52O2

CAS 号

2189-80-2

中文名称

醋酸蒲公英霜

结构分类
  • Terpenoids
  • Triterpenes
来源
  • Plants
  • Compositae
  • Taraxacum mongolicumHand.-Mazz.
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.