COX-2-IN-24

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COX-2-IN-24

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2417995-10-7

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

COX-2-IN-24 是一种有口服活性的COX-2抑制剂，IC₅₀值为 0.17 μM，表现出抗炎和低致溃疡活性。

生物活性

COX-2-IN-24 is an orally active inhibitor ofCOX-2withIC₅₀value of 0.17 μM, shows anti-inflammatory and low ulcerogenic activities.

IC₅₀& Target

COX-2

0.17 μM (IC₅₀)

体内研究
(In Vivo)

COX-2-IN-24 (Intraperitoneal injection; 9mg/100g; once an hour; 4 hours) shows anti-inflammatory activity in the carrageenan-induced rat paw edema model^[1].
COX-2-IN-24 (Oral gavage; 9mg/100g; once a day; 3 days) shows low ulcerogenic activity in the received 1% gum acacia (suspending vehicle) orally male albino rats model^[1].

Animal Model:	Mature male albino rats^[1]
Dosage:	9mg/100g
Administration:	Intraperitoneal injection; 9mg/100g; once an hour; 4 hours
Result:	Exhibited a promising anti-inflammatory activity in the carrageenan-induced rat paw edema model.

Animal Model:	Mature male albino rats^[1]
Dosage:	9mg/100g
Administration:	Oral gavage; 9mg/100g; once a day; 3 days
Result:	Exhibited low ulcerogenic activity in the received 1% gum acacia (suspending vehicle) orally male albino rats model.

分子量

574.51

Formula

C₂₄H₂₄BrN₅O₃S₂

CAS 号

2417995-10-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.