| CAS NO: | 312-84-5 |
| 包装 | 价格(元) |
| 25g | 电议 |
| 100g | 电议 |
| Cas No. | 312-84-5 |
| 别名 | D-丝氨酸; (R)-Serine |
| 化学名 | (2R)-2-amino-3-hydroxypropanoic acid |
| Canonical SMILES | C(C(C(=O)O)N)O |
| 分子式 | C3H7NO3 |
| 分子量 | 105.09 |
| 溶解度 | PBS (pH 7.2): 5mg/mL |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (R)-Serine, an endogenous amino acid involved in glia-synapse interactions that has unique neurotransmitter characteristics, is a potent co-agonist at the NMDA glutamate receptor. (R)-Serine has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration[1][2]. (R)-Serine is synthesized from L-Ser by serine racemase (SR) and degraded by D-amino acid oxidase (DAAO) and SR. Distribution of D-Ser and NMDAR as determined by chemical measurement and immunohistochemistry supports D-Ser as an endogenous coagonist acting on the glycine modulatory site of the NR1 subunits of the NMDAR[3]. (R)-Serine (10 g/L; p.o.; throughout 8 weeks) regulates HFD induced weight gain[4]. References: |
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