CAS NO: | 123226-28-8 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | CAY10789 (compound 6) is a potentCysLT1R(cysteinylleukotriene receptor1) antagonist (IC50=2.80 μM) andGPBAR1(G-protein-coupled bile acid receptor 1) agonist (EC50=3 μM). CAY10789 significantly reduces the adhesion of U937 cells to HAEC, reduces the expression of TNF-α. CAY10789 shows very promising metabolic stability and excellent pharmacokinetics. CAY10789 can be used for the research of colitis, metabolic syndromes, and other GPBAR1/CysLT1R-related diseases[1]. | |
IC50& Target |
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分子量 | 265.31 | |
Formula | C17H15NO2 | |
CAS 号 | 123226-28-8 | |
运输条件 | Room temperature in continental US; may vary elsewhere. | |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |