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Sarafotoxin S6a TFA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Sarafotoxin S6a TFA 是一种 Sarafotoxin 类似物,是一种内皮素受体 (endothelin receptor) 激动剂,具有与 Endothelin-3 (HY-P0204) 相似的ETA/ETB选择性。Sarafotoxin S6a TFA 诱导猪冠状动脉的EC50值为 7.5 nM。
生物活性

Sarafotoxin S6a TFA , a sarafotoxin analogue, is aendothelin receptoragonist and has anETA/ETBselectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a TFA elicits the pig coronary artery with anEC50 value of 7.5 nM[1].

IC50& Target[1]

ETB

 

ETA

 

体外研究
(In Vitro)

Sarafotoxin S6a TFA is a rather weak agonist effect in guinea-pig aorta, the eliting concentration (EC50) is 150 nM in guinea-pig aorta.

分子量

2628.87

Formula

C107H157F3N28O36S5

Sequence

Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp (Disulfide bridge:Cys1-Cys15;Cys3-Cys11)

Sequence Shortening

CSCKDMTDKECLNFCHQDVIW (Disulfide bridge:Cys1-Cys15;Cys3-Cys11)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

溶解性数据
In Vivo:
  • 1.

    S6a is dissolved in 0.1% aqueous acetic acid and diluted in 0.9% NaCl[1].