Elubrixin (SB-656933) is a potent, selective, competitive, reversible and orally activeCXCR2antagonist and anIL-8receptorantagonist. Elubrixin inhibits neutrophil CD11b upregulation (IC₅₀of 260.7 nM) and shape change (IC₅₀of 310.5 nM). Elubrixin has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation^[1][2][3].

Elubrixin has an inhibitory effect on neutrophils in a dose-dependent fashion^[1].

463.31

C₁₇H₁₇Cl₂FN₄O₄S

688763-64-6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.