CXCR4 modulator-2

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CXCR4 modulator-2

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2488943-55-9

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

CXCR4 modulator-2 (compound Z7R) 是一种高效的CXCR4调节剂，IC₅₀为 1.25 nM。CXCR4 modulator-2 在小鼠血清中具有可接受的稳定性 (t_1/2= 77.1 min)，在小鼠水肿模型中表现出抗炎活性。

生物活性

CXCR4modulator-2 (compound Z7R) is a highly potentCXCR4modulator with anIC₅₀value of 1.25 nM.CXCR4modulator-2 has acceptable stability (t_1/2= 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model^[1].

IC₅₀& Target^[1]

CXCR4

1.25 nM (IC₅₀)

体内研究
(In Vivo)

CXCR4 modulator-2 (10 mg/kg; IP; single dosage) significantly reduces the edema weights (~50%) in the lesion and decreases the expression of CXCR4s^[1].

Animal Model:	male nude mice (6 weeks, 20 g; subcutaneous injection of 50 μL of λ-carrageenan)^[1]
Dosage:	10 mg/kg
Administration:	IP; single dosage
Result:	Significantly reduced the edema weights (~50%) in the lesion and decreased the expression of CXCR4s.

分子量

428.53

Formula

C₂₁H₃₂N₈O₂

CAS 号

2488943-55-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.