Plerixafor-d4 is the deuterium labeled Plerixafor. Plerixafor (AMD 3100) is a selectiveCXCR4antagonist with anIC₅₀of 44 nM. Plerixafor, an immunostimulant and ahematopoietic stem cell (HSC)mobilizer, is an allosteric agonist ofCXCR7. Plerixafor inhibitsHIV-1andHIV-2replication with anEC₅₀of 1-10 nM^{[1][2][3][4][7]}.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

506.81

C₂₈H₅₀D₄N₈

1246819-87-3

普乐沙福 d4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.