CAS NO: | 447459-51-0 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | SCH 336 is a potent, selective, inverse and orally activeCB2agonist. SCH 336 inhibits BaF3/CB2 migration. SCH 336 significantly inhibits the migration of leukocytes in vivo. SCH 336 blocks ovalbumin-induced lung eosinophilia in mice[1]. | ||||||||
IC50& Target[1] |
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体外研究 (In Vitro) | SCH 336 (Sch.336) (0-10 μM) competes with [3H]CP55,940 for binding to human CB2 on Sf9 cell membranes with Kiof 1.8 nM, and decreases GTPγS binding on human CB2-containing membranes with an EC50of 2 nM, decreases potency on CB1-containing membranes with EC50of 200 nM[1]. | ||||||||
体内研究 (In Vivo) | SCH 336 (0.02, 0.2, 2.0 mg/kg; i.p.) significantly inhibits the migration of leukocytes[1].
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分子量 | 539.64 | ||||||||
Formula | C23H25NO8S3 | ||||||||
CAS 号 | 447459-51-0 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |