| CAS NO: | 190967-35-2 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 20mg | 电议 |
| Cas No. | 190967-35-2 |
| Canonical SMILES | CS(=O)(NC1=CC=C(OC2=CC=C(F)C=C2)S1)=O |
| 分子式 | C11H10FNO3S2 |
| 分子量 | 287.33 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | RWJ 63556 is an orally active COX-2 selective/5-lipoxygenase inhibitor, with anti-inflammatory activities. RWJ 63556 is a potent inhibitor of leukocyte influx over a period of 24 hr and maintains its in vitro profile on eicosanoids[1]. RWJ 63556 (1 mg/kg, i.v.) significantly inhibits the development of SP-induced oedema[2]. [1]. Kirchner T, et al. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation. J Pharmacol Exp Ther. 1997 Aug;282(2):1094-101. [2]. Le Filliatre G, et al. Cyclo-oxygenase and lipoxygenase pathways in mast cell dependent-neurogenic inflammation induced by electrical stimulation of the rat saphenous nerve. Br J Pharmacol. 2001 Apr;132(7):1581-9. |
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