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Globotetraosylceramides(porcine RBC)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Globotetraosylceramides(porcine RBC)图片
CAS NO:11034-93-8
包装:5mg
市场价:7545元

产品介绍
Cas No.11034-93-8
别名红细胞糖苷脂
Canonical SMILESOC[C@H]1O[C@@H](OC[C@H](NC([R])=O)[C@H](O)/C=C/CCCCCCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O[C@]2([H])O[C@H](CO)[C@H](O[C@@]3([H])O[C@H](CO)[C@H](O)[C@H](O[C@]4([H])O[C@H](CO)[C@H](O)[C@H](O)[C@H]4NC(C)=O)[C@H]3O)[C@H](O)[C@H]2O
分子式C68H126N2O23(for tetracosanoyl)
分子量1339.7
溶解度Chloroform:Methanol (2:1): Soluble,DMSO: Soluble,Methanol: Warmed
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes. They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, and parvovirus B19. Globotetraosylceramides increase the expression of proteins responsible for enamel deposition, including ameloblastin, amelogenin, and enamelin, in dental epithelial cells and activate the ERK and p38 MAPK signaling pathways. Levels of globotetraosylceramides are elevated in fibroblasts from patients with salt and pepper syndrome, a neurocutaneous condition characterized by intellectual disability and hyper- and hypo-pigmented skin. Globotetraosylceramides (porcine RBC) contains a mixture of globotetraosylceramides with variable fatty acyl chain lengths isolated from porcine red blood cells.