O-2050 is a high affinitycannabinoid CB₁receptorantagonist with aK_iof 2.5 nM. O-2050 inhibits cannabinoid CB₂receptor (K_i=0.2 nM). O-2050 can cause locomotor stimulation in mice^[1].

O-2050 (1, 3, 10, 30 mg/kg; ip; pretreatment 30 mins) produces significant and dose-dependent decreases in food intake in mice. O-2050 (10, 30 mg/kg) significantly causes locomotor stimulation^[1].

417.56

C₂₃H₃₁NO₄S

1883545-42-3

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