Angiotensin III, human, mouse is a heptapeptide, acts as an endogenousangiotensin type 2 receptor (AT₂R)agonist, withIC₅₀s of 0.648 nM and 21.1 nM for AT₂R and AT₁R, respectively.

IC50: 0.648 nM (AT₂R), 21.1 nM (AT₁R)^[1]

Angiotensin III, human, mouse is a heptapeptide, acts as an endogenous angiotensin type 2 receptor (AT₂R) agonist, with IC₅₀s of 0.648 nM and 21.1 nM for AT₂R and AT₁R, respectively^[1].

Angiotensin III (7, 14 and 28 nmol/kg/min) increases urine sodium excretion (U_NaV), fractional excretion of sodium (FE_Na), and fractional excretion of lithium (FE_Li) in SD rat^[2]. In RAS (renin-angiotensin system), Angiotensin III increases sympathetic nerve activity and vasopressin release and decreases the baroreflex leading to higher blood pressure in rats^[3].

931.09

Solid

C₄₆H₆₆N₁₂O₉

13602-53-4

Arg-Val-Tyr-Ile-His-Pro-Phe

RVYIHPF

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

H₂O : 100 mg/mL(107.40 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。