Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, is a weaksst₂/sst₅receptor partial agonist withIC₅₀values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA is a potent inhibitor of growth hormone release andinsulin-like growth factor-1 (IGF-1)production. Angiopeptin TFA inhibitsadenylate cyclaseor stimulates extracellular acidification. Angiopeptin TFA has the potential for coronary atherosclerosis research^[1][2].

IC50: 0.26 nM (sst2) and 6.92 nM (sst5)^[1][2]

Angiopeptin (0.1 nM- 10 μM; for 1 h) TFA acts as a partial agonist (pEC₅₀=6.57) with a maximum response of 423% at 3 μM on the release of tritium on CHO hsst₂cells^[2].

Angiopeptin (20 and 50μg/kg; i.h.) TFA significantly inhibits neointimal formation^[1].
Angiopeptin (20 μg/kg; per day) TFA significantly inhibits coronary artery myointimal proliferation in cardiac allografts by appmximalely 50%^[1].

1326.39

Solid

C₅₈H₇₃F₆N₁₁O₁₄S₂

2478421-60-0

{Nal}CYWKVCT-NH2

血管抑肽三氟乙酸盐

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

H₂O : 10 mg/mL(7.54 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。