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Clocapramine dihydrochloride hydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Clocapramine dihydrochloride hydrate图片
CAS NO:60789-62-0
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
3-Chlorocarpipramine dihydrochloride hydrate
产品介绍
Clocapramine hydrochloride hydrate 是多巴胺D25-HT2A受体拮抗剂。
生物活性

Clocapramine hydrochloride hydrate is an antagonist of theD2and5-HT2Areceptors.

IC50& Target

D2Receptor

 

5-HT2AReceptor

 

体内研究
(In Vivo)

Clocapramine shows the lowest potency for D2-occupancy in vivo[1]. An in vivo receptor binding technique is used to evaluate the binding profiles of typical and atypical antipsychotic drugs to striatal dopamine-D2and frontal serotonin-5-HT2receptors in a rat brain using more specific ligands. Clocapramine produces ratios of potency in occupying 5-HT2versus D2receptors that fall between these two groups (ED50of 14.5 mg/kg for D2, 4.9 mg/kg for 5-HT2)[2].

分子量

572.01

Formula

C28H41Cl3N4O2

CAS 号

60789-62-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.