Cisapride monohydrate

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

260779-88-2

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品名称

R 51619 monohydrate
(±)-Cisaprid monohydrate

产品介绍

Cisapride monohydrate 是一种口服有效的5-HT₄受体激动剂和hERG抑制剂。Cisapride monohydrate 是一种促动力剂，促进或恢复整个胃肠道的运动。Cisapride monohydrate 通过肠肌间神经丛中节后神经末梢释放乙酰胆碱的间接机制刺激胃肠道运动活动。

生物活性

Cisapride monohydrate is an orally and potent5-HT₄receptor agonist andhERGinhibitor. Cisapride monohydrate is an prokinetic agent which facilitates or restores motility throughout the length of the gastrointestinal tract. Cisapride monohydrate stimulates gastrointestinal motor activity through an indirect mechanism involving the release of acetylcholine mediated by postganglionic nerve endings in the myenteric plexus of the gut^[1]^[2].

IC₅₀& Target

5-HT₄Receptor

0.14 μM (EC₅₀)

Clinical Trial

分子量

483.96

Formula

C₂₃H₃₁ClFN₃O₅

CAS 号

260779-88-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.