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Piperaquine phosphate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:85547-56-4
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Description: Piperaquine phosphate, a bisquinoline analog, is a potent antiparasitic agent that has been widely used in combination with other antimalarial agents such as dihydroartemisinin to treat malaria. Piperaquine was developed under the Chinese National Malaria Elimination Programme in the 1960s and was adopted throughout China as a replacement for the structurually similar antimalarial drug chloroquine. Due to widespread parasite resistance to piperaquine, the drug fell out of use as a monotherapy, and is instead used as a partner drug for artemisinin combination therapy. Piperaquine kills parasites by disrupting the detoxification of host heme. References: Fivelman QL, et al. Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains. Antimicrob Agents Chemother. 2007 Jun;51(6):2265-7. Related CAS: 911061-10-4 (Piperaquine tetraphosphate); 85547-56-4 (Piperaquine monophosphate)

纯度:≥98%

CAS:85547-56-4