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Iclaprim(AR-100)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Iclaprim(AR-100)图片
CAS NO:192314-93-5
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1mg电议
5mg电议
10mg电议
50mg电议
100mg电议

产品介绍
Iclaprim (AR-100) 是一种新型选择性细菌二氢叶酸抑制剂,可抑制金黄色葡萄球菌的生长。
Cas No.192314-93-5
别名艾拉普林,AR-100
Canonical SMILESNC1=NC=C(CC2=C3C=CC(C4CC4)OC3=C(OC)C(OC)=C2)C(N)=N1
分子式C19H22N4O3
分子量354.4
溶解度DMSO : 30 mg/mL (84.65 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.

Iclaprim inhibits the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL[2].

[1]. Schneider P, et al. Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4217-21. [2]. Kohlhoff SA, et al. Iclaprim. Expert Opin Investig Drugs. 2007 Sep;16(9):1441-8.