8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide is a potent and selective5-HT_1Aagonist with apIC₅₀of 8.19. 8-OH-DPAT hydrobromide has selectivity of almost 1000 fold for a subtype of the 5-HT₁binding site^[1].

8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide has no effect on 5-HT_1Bbinding at concentrations lower than 100 nM^[1].

8-OH-DPAT (8-Hydroxy-DPAT) hydrobromide (32, 56, 80, 100 mg/kg; intramuscularly; 15 min prior to the testing session) of the highest dose significantly interferes with sustained attention and reinforcer efficacy (progressive ratio; PR) performance in the 3,4-methylenedioxymethamphetamine (MDMA)-exposed but not control animals^[1].

328.29

Solid

C₁₆H₂₆BrNO

76135-31-4

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

DMSO : 25 mg/mL(76.15 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。