CAS NO: | 219984-49-3 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
生物活性 | Revexepride is a highly selective5-HT4 receptoragonist, and a potential inducer ofCYP3A4 enzyme, used for the treatment of gastroesophageal reflux disease. | ||||||||||||||||
IC50& Target |
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体外研究 (In Vitro) | The human CYP isoenzymes are involved in the metabolism of revexepride, which is mainly metabolized in vitro in humans by CYP3A4 (99.9%) with a minor contribution of CYP2D6 (0.1%). Revexepride exhibits direct inhibition of human CYP3A4 in vitro with IC50values of 16-49 μM[1]. | ||||||||||||||||
分子量 | 425.95 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C21H32ClN3O4 | ||||||||||||||||
CAS 号 | 219984-49-3 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : ≥ 100 mg/mL(234.77 mM) *"≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |