SIRT2-IN-9 (compound 12) is a selective inhibitor ofSRIT2with anIC₅₀value of 1.3 μM. SIRT2-IN-9 inhibits proliferative activity of MCF-7 breastcancercells. SIRT2-IN-9 can be used for the research ofcancer^[1].

SIRT2-IN-9 (1-100 μM; 15 min) dose-dependently inhibits SRIT2 with an IC₅₀value of 1.3 μM, and inhibits SRIT1 and SRIT3 with IC₅₀s ＞300 μM^[1].
SIRT2-IN-9 (0-50 μM; 72 h) affects cell viability of MCF-7 cells^[1].
SIRT2-IN-9 (0-50 μM; 6 h) affects acetylation of α-tubulin protein^[1].

438.57

Solid

C₂₁H₂₂N₆OS₂

522650-91-5

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

DMSO : 4.46 mg/mL(10.17 mM;ultrasonic and warming and heat to 70℃)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (protect from light)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。