Verminoside

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Verminoside

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

50932-19-9

包装与价格：

包装	价格(元)
5mg	电议
10mg	电议
25mg	电议

产品介绍

Verminoside 是从Kigelia africana分离出的一种环烯醚萜，具有抗炎和显着的抗氧化活性，其自由基清除活性为 2.5 μg/mL。Verminoside 对人淋巴细胞的遗传毒性与PARP-1和p53蛋白水平升高有关。

生物活性

Verminoside is an iridoid isolated fromKigelia africana, exhibits anti-inflammatory and remarkable antioxidant activity with a radical-scavenging activity of 2.5 μg/mL. The genotoxicity of Verminoside on human lymphocytes is associated with elevated levels ofPARP-1andp53proteins^[1]^[2]^[3].

IC₅₀& Target^[2]

PARP-1

体外研究
(In Vitro)

Verminoside (Compound 1; 0.01-1 mM; 25 hours; J774.A1 macrophages) treatment shows significant and concentration-related inhibition of iNOS expression at 0.1 mM and 1 mM in LPS-stimulated J774.A1 macrophages^[1].

Western Blot Analysis^[1]

Cell Line:	J774.A1 macrophages
Concentration:	0.01 mM, 0.1 mM or 1 mM
Incubation Time:	25 hours
Result:	Showed significant and concentration-related inhibition of iNOS expression at 0.1 mM and 1 mM in LPS-stimulated J774.A1 macrophages.

分子量

524.47

Formula

C₂₄H₂₈O₁₃

CAS 号

50932-19-9

结构分类

Terpenoids
Iridoids

Phenols
Polyphenols

来源

Plants
other families

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.