| CAS NO: | 2280037-51-4 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 生物活性 | Bobcat339 is a potent and selective cytosine-based inhibitor ofTET enzyme, withIC50s of 33 μM and 73 μM forTET1andTET2, respectively. Bobcat339 is useful to the field ofepigeneticsand serves as a starting point for new therapeutics that target DNA methylation and gene transcription[1]. |
| IC50& Target | IC50: 33 μM (TET1); 73 μM (TET2)[1] |
| 体外研究 (In Vitro) | Bobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells[1]. |
| 分子量 | 297.74 |
| Formula | C16H12ClN3O |
| CAS 号 | 2280037-51-4 |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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