AMPK activator 8

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AMPK activator 8

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1852451-96-7

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

AMPK activator 8 (compound 2) 是一种 AMP 激活的蛋白激酶 (AMPK)激活剂，对 rAMPK α1β1γ1、rAMPK α2β1γ1、rAMPK α1β2γ1、rAMPK α2β2γ1、rAMPK α2β2γ3 的EC₅₀分别为 11、27、4、2 和 4 nM。AMPK activator 8 可用于 2 型糖尿病的研究。

生物活性

AMPK activator8 (compound 2) is an AMP-activated protein kinase (AMPK) activator withEC₅₀s of 11, 27, 4, 2, and 4 nM for rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ1, rAMPK α2β2γ3, respectively.AMPK activator8 can be used for the research of type 2 diabetes^[1].

IC₅₀& Target

AMPK α1β1γ1

11 nM (EC₅₀)

AMPK α2β1γ1

27 nM (EC₅₀)

AMPK α1β2γ1

4 nM (EC₅₀)

AMPK α2β2γ1

2 nM (EC₅₀)

体外研究
(In Vitro)

AMPK activator 8 (compound 2) acts on rAMPK α1β1γ1, rAMPK α2β1γ1, rAMPK α1β1γ1, rAMPK α1β2γ1, rAMPK α2β2γ and rAMPK α2β2γ3 with the EC₅₀value of 11 nM, 27 nM, 4 nM, 2 nM and 4 nM, respectively^[1].
AMPK activator 8 (compound 2) affects cell viability^[1].

Cell Viability Assay^[1]

Cell Line:	HepG2, C2C12 myoblasts
Concentration:	0.01-1000 μM
Incubation Time:	1 hour
Result:	Resulted in HepG2 and C2C12 myoblasts with the EC₅₀value of 255 nM and 230 nM, respectively.

分子量

480.90

Formula

C₂₅H₂₁ClN₂O₆

CAS 号

1852451-96-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.