| CAS NO: | 2095432-71-4 |
| 包装 | 价格(元) |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 生物活性 | GSK269962A hydrochloride (GSK 269962 hydrochloride) is a potentROCKinhibitor withIC50s of 1.6 and 4 nM for recombinant humanROCK1andROCK2respectively. GSK269962A hydrochloride has anti-inflammatory and vasodilatory activities[1]. | |||||||||
| IC50& Target[1] |
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| 体外研究 (In Vitro) | GSK269962A has an IC50of 1.6 nM toward recombinant human ROCK1. GSK269962A exhibits more than 30-fold selectivity against a panel of serine/threonine kinases[1]. | |||||||||
| 体内研究 (In Vivo) | GSK269962A is a potent antihypertensive agent. GSK269962A (0.3, 1, and 3 mg/kg; oral gavage) induces a dose-dependent reduction in blood pressure in spontaneously hypertensive rat (SHR). The reduction of blood pressure is acute and substantial[1].
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| 分子量 | 607.06 | |||||||||
| Formula | C29H31ClN8O5 | |||||||||
| CAS 号 | 2095432-71-4 | |||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
| 储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |
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