Fingolimod-d4 (FTY720 free based-d4) is the deuterium labeled Fingolimod. Fingolimod (FTY720 free base) is asphingosine 1-phosphate(S1P) antagonist with anIC₅₀of 0.033 nM in K562 and NK cells. Fingolimod also is apak1activator, a immunosuppressant^[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

311.50

C₁₉H₂₉D₄NO₂

1346747-38-3

芬戈莫德 d4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.