HA-100 hydrochloride is a potentprotein kinaseinhibitor, withIC₅₀s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) andMLC-kinase, respectively. HA-100 hydrochloride also used as aROCKinhibitor^[1][2].

HA-100 hydrochloride inhibits MLC-kinase and PKC competitively with respect to ATP, with K_is of 61 and 6.5 μM, respectively^[1].

313.80

C₁₃H₁₆ClN₃O₂S

141543-63-7

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.