Colchicine-d6 is the deuterium labeled Colchicine. Colchicine is atubulininhibitor and amicrotubuledisrupting agent. Colchicine inhibits microtubule polymerization with anIC₅₀of 3 nM^[1][2][3]. Colchicine is also a competitive antagonist of theα3 glycine receptors(GlyRs)^[4].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

405.47

C₂₂H₁₉D₆NO₆

1217651-73-4

秋水仙素 d6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.