CAS NO: | 1126721-79-6 |
包装 | 价格(元) |
2.5mg | 电议 |
1mg | 电议 |
25mg | 电议 |
生物活性 | Sunitinib-d4 (SU 11248-d4) is the deuterium labeled Sunitinib. Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase inhibitor withIC50s of 80 nM and 2 nM forVEGFR2andPDGFRβ, respectively[1]. Sunitinib, an ATP-competitive inhibitor, effectively inhibits autophosphorylation ofIre1αby inhibiting autophosphorylation and consequent RNase activation[2]. |
体外研究 (In Vitro) | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
分子量 | 402.50 |
Formula | C22H23D4FN4O2 |
CAS 号 | 1126721-79-6 |
中文名称 | 舒尼替尼 d4 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |